Blog

Technology Obsolescence

Preclinical

Technology Obsolescence

Exhausted T cells

Preclinical

Exhausted T cells

Lost in Translation: Detection of mRNA by Flow Cytometry

Preclinical

Lost in Translation: Detection of mRNA by Flow Cytometry

Using Flow Cytometry to Characterize Myeloid Derived Suppressor Cells (MDSC)

Preclinical

Using Flow Cytometry to Characterize Myeloid Derived Suppressor Cells (MDSC)

Measuring Innate Immune/Phagocytic Cell Function by Flow Cytometry

Preclinical

Measuring Innate Immune/Phagocytic Cell Function by Flow Cytometry

Immunophenotyping Pig Immune Cells by Flow Cytometry

Preclinical

Immunophenotyping Pig Immune Cells by Flow Cytometry

The Thing About Theranostics…

Clinical

The Thing About Theranostics…

American Association of Pharmaceutical Scientists (AAPS) Flow Cytometry Action Programming Committee

Preclinical

American Association of Pharmaceutical Scientists (AAPS) Flow Cytometry Action Programming Committee

Why Small Molecules Are Still a Big Deal

Clinical

Why Small Molecules Are Still a Big Deal

Profiling a Killer at the Scene of the Crime

Preclinical

Profiling a Killer at the Scene of the Crime

The Rising Impact of ADCs in Cancer Treatment

Clinical

The Rising Impact of ADCs in Cancer Treatment

A Brief History of Flow Cytometry

Preclinical

A Brief History of Flow Cytometry

Silent but Deadly, and Beneficial? – Natural Killer Cells

Preclinical

Silent but Deadly, and Beneficial? – Natural Killer Cells

The Basophil Activation Test: An Application of Flow Cytometry for Allergy Testing in Clinical Trials

Preclinical

The Basophil Activation Test: An Application of Flow Cytometry for Allergy Testing in Clinical Trials

Navigating the Preclinical-to-Clinical Transition for ADCs: Regulatory & Study Design Strategies

Regulatory, Preclinical

Navigating the Preclinical-to-Clinical Transition for ADCs: Regulatory & Study Design Strategies

Featured Guest Blog: Quality is Critical by Mary E. Lynn

Preclinical

Featured Guest Blog: Quality is Critical by Mary E. Lynn

Creating Consistent Results by Managing your Flow Cytometry Data

Preclinical, Flow

Creating Consistent Results by Managing your Flow Cytometry Data

Comparison of Different Fix/Permeabilization Buffers for use in Flow Cytometry Evaluations

Preclinical

Comparison of Different Fix/Permeabilization Buffers for use in Flow Cytometry Evaluations

Quantification of Regulatory T Cells in Mouse Tumor Specimens Using Flow Cytometry

Preclinical, Flow

Quantification of Regulatory T Cells in Mouse Tumor Specimens Using Flow Cytometry

A Science Driven Approach: Translating Preclinical ADC Insights into Clinical Success

Clinical

A Science Driven Approach: Translating Preclinical ADC Insights into Clinical Success

Controls in Flow Cytometry

Preclinical

Controls in Flow Cytometry

The Cost of Delay: Quantifying the Financial Impact of Inefficient Clinical Trial Start-Up

Regulatory, Clinical

The Cost of Delay: Quantifying the Financial Impact of Inefficient Clinical Trial Start-Up

TD2 Routine Analysis and More

Preclinical

TD2 Routine Analysis and More

Specimen Stability Considerations During Flow Cytometry Assay Development, Optimization and Validation

Preclinical

Specimen Stability Considerations During Flow Cytometry Assay Development, Optimization and Validation

Fluorescent Cell Barcoding Using Flow Cytometry For High Throughput Testing

Preclinical

Fluorescent Cell Barcoding Using Flow Cytometry For High Throughput Testing

Flow Cytometry Processing and Analysis of Tumor Specimens: Testing Viability and Staining Post Shipping

Preclinical

Flow Cytometry Processing and Analysis of Tumor Specimens: Testing Viability and Staining Post Shipping

The Importance of Conducting PDX Oncology Studies in a Humanized Immune System

Preclinical

The Importance of Conducting PDX Oncology Studies in a Humanized Immune System

Leveraging Flow Cytometry to Drive Better Patient Outcomes in Hematologic Malignancy Clinical Trials

Clinical

Leveraging Flow Cytometry to Drive Better Patient Outcomes in Hematologic Malignancy Clinical Trials

The Importance of Incorporating Metabolomic and Proteomic Screening in Preclinical Oncology Studies

Preclinical

The Importance of Incorporating Metabolomic and Proteomic Screening in Preclinical Oncology Studies

Challenges in Radiopharmaceutical Development for Oncology Therapies

Clinical

Challenges in Radiopharmaceutical Development for Oncology Therapies

Emerging Trends in Radiopharmaceuticals

Clinical

Emerging Trends in Radiopharmaceuticals

Optimizing Site Selection for Faster Patient Enrollment in Oncology Trials

Clinical

Optimizing Site Selection for Faster Patient Enrollment in Oncology Trials

Choosing the Right DIO Mouse Model for Your Oncology Study

Preclinical

Choosing the Right DIO Mouse Model for Your Oncology Study

Navigating the Complexities of Clinical Trial Start-Up

Regulatory, Clinical

Navigating the Complexities of Clinical Trial Start-Up

Harnessing the Capabilities of Aura Imaging Software 4.0 in Preclinical Oncology Research

Preclinical

Harnessing the Capabilities of Aura Imaging Software 4.0 in Preclinical Oncology Research

Predictive Value of CDX Models: Bridging Preclinical and Clinical Research

Preclinical

Predictive Value of CDX Models: Bridging Preclinical and Clinical Research

Unlocking the Potential: Optical Luminescence vs. Fluorescence Imaging in Preclinical Oncology Research

Preclinical

Unlocking the Potential: Optical Luminescence vs. Fluorescence Imaging in Preclinical Oncology Research

Top Trends in ADC Drug Development

Preclinical

Top Trends in ADC Drug Development

Unlocking Insights: Top 5 Reasons to Incorporate Orthotopic GBM PDX Models into Your Preclinical Evaluation

Preclinical

Unlocking Insights: Top 5 Reasons to Incorporate Orthotopic GBM PDX Models into Your Preclinical Evaluation

The Vital Role of Highly Characterized Glioblastoma PDX Models in Preclinical Cancer Research: Insights from TD2's Most Recent Studies

The Vital Role of Highly Characterized Glioblastoma PDX Models in Preclinical Cancer Research: Insights from TD2's Most Recent Studies

 

Preclinical

Enhancing Immuno-Oncology Research: Top 5 Essential Flow Cytometry Assays

Climbing the Mountain: Current Challenges in Early Phase Oncology Clinical Trials

Clinical

Climbing the Mountain: Current Challenges in Early Phase Oncology Clinical Trials

The Significance of Preclinical Evaluation in CAR T-cell Therapy for Solid and Hematologic Tumors

Preclinical

The Significance of Preclinical Evaluation in CAR T-cell Therapy for Solid and Hematologic Tumors

Advancing Preclinical Cancer Research Through Metabolomics: Key Strategies for Biomarker Identification and Drug-Target Analysis in Immuno-Oncology

Preclinical

Advancing Preclinical Cancer Research Through Metabolomics: Key Strategies for Biomarker Identification and Drug-Target Analysis in Immuno-Oncology

Orthotopic vs. Subcutaneous: Unpacking the Strengths and Limitations of Tumor Model Implantation Sites

Preclinical

Orthotopic vs. Subcutaneous: Unpacking the Strengths and Limitations of Tumor Model Implantation Sites

Unveiling the Potential: 5 Ways DIO Mice Enhance Immuno-Oncology Discoveries

Preclinical

Unveiling the Potential: 5 Ways DIO Mice Enhance Immuno-Oncology Discoveries

Rule-Based Approach in Early-Phase Oncology

Clinical

Rule-Based Approach in Early-Phase Oncology

Genetically Engineered Humanized Mouse Models: A Critical Tool for Studying Immunotherapy Drugs

Preclinical

Genetically Engineered Humanized Mouse Models: A Critical Tool for Studying Immunotherapy Drugs

Diet-Induced Obesity Tumor Models for Cancer Studies

Preclinical

Diet-Induced Obesity Tumor Models for Cancer Studies

LAB in focus: Leuconostoc mesenteroids in Health and Industry

Microbiome Monday

LAB in focus: Leuconostoc mesenteroids in Health and Industry

The A-Z Guide of DMPK Assays and How to Find the Right One

The A-Z Guide of DMPK Assays and How to Find the Right One

Early Phase Oncology Trial Designs: Model-Based Approach

Clinical

Early Phase Oncology Trial Designs: Model-Based Approach

Early Phase Oncology Trial Designs: The Model-Assisted Approach

Clinical

Early Phase Oncology Trial Designs: The Model-Assisted Approach

Butyrate production by Bifidobacterium bifidum

Microbiome Monday

Butyrate production by Bifidobacterium bifidum

L.helveticus: A lactobacilli for cancer treatment

Microbiome Monday

L.helveticus: A lactobacilli for cancer treatment

Probiotics in focus: How does L. reuteri affect gut health?

Microbiome Monday

Probiotics in focus: How does L. reuteri affect gut health?

CAR T-cell Therapy Program Development: Key Considerations

Preclinical

CAR T-cell Therapy Program Development: Key Considerations

Efficient Data Management: One Way to Expedite the Clinical Development Process

Clinical

Efficient Data Management: One Way to Expedite the Clinical Development Process

 

Clinical

The Clinical Trial Process Continues Amid COVID-19

 

Clinical

Technology Challenges and Trends in Clinical Trials

 

Preclinical

Maximizing Reproducibility in Cancer Research

 

Preclinical

Will Your Cancer Drug Move Past Phase 1?

 

Preclinical

The Missing Step Between Phase I and Phase II

 

Preclinical

Now Available: Liver Fibrosis Models Fed Choline-Deficient, High-Fat Diets

 

Preclinical

The Keto Diet and Cancer Research: New Insights Emerge

The Critical Significance of DMPK Studies in Preclinical Research

PK/ADME

The Critical Significance of DMPK Studies in Preclinical Research

 

Preclinical

In Vitro vs. In Vivo Preclinical Drug Testing

 

Regulatory

Oncology Drug Approval Process

 

Preclinical

Future Trends for Oncology Drug Development

 

Clinical

The Top 5 Challenges in Oncology Drug Development

 

Clinical

Move your research forward, smarter with TD2

 

Clinical

Your Guide to a Smart Clinical Strategy

 

Preclinical

Research Review: 4 Secrets for Preclinical Success

 

Regulatory

What is the Difference Between Research and Commercial IND Categories?

 

Regulatory

What are the Types of INDs?